Lab Notes: Milk Does a Pancreas Good
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(MedPage Today) -- This week in Lab Notes, discover how milk may rejuvenate pancreatic islet cells to help manage diabetes. Plus the "dumbing" effects of anesthesia and curing well groomed mice with OCD. (Source: MedPage Today Endocrinology)
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Incretin Talk Continues at ENDO Meeting
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SAN FRANCISCO (MedPage Today) -- As the debate over pancreatic risks with incretin therapies for type 2 diabetes comes to a boil, it's likely to be the topic of much discussion at this year's meeting of the Endocrine Society. (Source: MedPage Today Cardiovascular)
Pancreatic Cancer and Incretins: No Signal as Yet at NIDDKPancreatic Cancer and Incretins: No Signal as Yet at NIDDK
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A definitive answer on whether there is an increased risk of pancreatic cancer with incretin diabetes drugs is still some years away, said dozens of experts at the NIDDK this week. Medscape Medical News (Source: Medscape Today Headlines)
Quick Postmeal Walks Better Than Once-Daily Longer OnesQuick Postmeal Walks Better Than Once-Daily Longer Ones
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In older adults with impaired fasting glucose, only postmeal exercise reduced after-dinner glycemia. Medscape Medical News (Source: Medscape Today Headlines)
Longer Acting GLP-1 Agonists and Improved CV OutcomesLonger Acting GLP-1 Agonists and Improved CV Outcomes
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Not only do GLP-1 receptor agonists reduce weight and A1c levels, but they also may improve cardiac parameters. Expert Review of Endocrinology and Metabolism (Source: Medscape Today Headlines)
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Dad's life stress exposure can affect offspring brain development, Penn Study finds (EurekAlert, 12 June 2013)
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A US study published in Journal of Neuroscience compares the stress response in the offspring of male mice exposed to stress at the preadolescent and adult stages, and investigates potential mechanisms taking place at fertilisation. Full article (Source: Society for Endocrinology)
Men 'to blame for the menopause' (BBC News Online, 14 June 2013)
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A paper in PLOS Computational Biology uses a computational model of deleterious mutation accumulation to propose a mechanism for the development of menopause could be caused by male mating preference. Full article (Source: Society for Endocrinology)
PhD Studentship in Breast Cancer Biology, Dublin, Eire
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Added via Naturejobs. A SFI funded PhD position is available within the Dept of Surgery, Royal College of Surgeons in Ireland. The Endocrine Oncology Research Group (EORG) within the Dept of Surgery focus on the molecular mechanisms underlying endocrine resistance in breast cancer. This project will investigate whether the steroid coactivator protein SRC-1 mediates reprogramming in individual cells to induce survival adaptability and drug resistance in human breast cancer. The successful candidate will be a highly motivated student with an upper second or first class honours degree in Biochemistry, Genetics or related subject. The research is multidisciplinary using a combination of standard molecular biology techniques, in vivo mouse models and clinical samples. The d...
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'Intersex' included on Australia's new gender guidelines (AFP, 14 June 2013)
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The Australian government has introduced new guidelines which recommend that personal records held by federal government departments and agencies should provide the option of selecting "male", "female" or "intersex". Full article (Source: Society for Endocrinology)
ADA Wants Firms to Disclose Incretin Data
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(MedPage Today) -- The American Diabetes Association is calling for makers of incretin therapies to release all of their data on the drugs in an effort to clarify whether they have adverse effects on the pancreas, the group said. (Source: MedPage Today Cardiovascular)
'Something for Everyone' on the Menu at ADA'Something for Everyone' on the Menu at ADA
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A plethora of presentations at the ADA Scientific Sessions this year should ensure that everyone involved in diabetes research and treatment will find something to whet their appetite. Medscape Medical News (Source: Medscape Today Headlines)
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The New Old Age: Price Reductions for Diabetes Care Supplies
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Medicare is reducing fees for diabetes care supplies, and beneficiaries are likely to be charged less, too. (Source: NYT Health)
Soda Ban Would Target Heavy Youth, Not Poor: StudySoda Ban Would Target Heavy Youth, Not Poor: Study
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A cap on soda size - such as the one New York City regulators are trying to pass - would have the biggest impact on overweight kids and young adults, a new study suggests. Reuters Health Information (Source: Medscape Medical News Headlines)
At-Home Weight Loss Programs for Kids Lack EvidenceAt-Home Weight Loss Programs for Kids Lack Evidence
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Programs designed to prevent childhood obesity in the home don't affect kids' weight a year or more down the line, according to a review of the evidence. Reuters Health Information (Source: Medscape Medical News Headlines)
Guidelines Key to Gestational Diabetes Dx (CME/CE)
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(MedPage Today) -- Differences in screening criteria for gestational diabetes are associated with large variations in the proportion of patients diagnosed with the condition, researchers found. (Source: MedPage Today Cardiovascular)
American Diabetes Association (ADA) 73rd Scientific Sessions®American Diabetes Association (ADA) 73rd Scientific Sessions®
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Read clinically focused news coverage of key developments from ADA 2013. Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
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Is There an Optimal Diet for Patients With Type 2 Diabetes?Is There an Optimal Diet for Patients With Type 2 Diabetes?
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Which diet is best for patients with type 2 diabetes? High protein, very low carbohydrate, or Mediterranean? The British Journal of Diabetes and Vascular Disease (Source: Medscape Today Headlines)
Cholesterol Metabolism After Bariatric Surgery in ObesityCholesterol Metabolism After Bariatric Surgery in Obesity
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Does gastric bypass surgery decrease cholesterol levels more than gastric banding? Diabetes Care (Source: Medscape Today Headlines)
Recognising low blood sugars could help prevent brain damage in newborn babies (AlphaGalileo, 12 June 2013)
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A UK study published in Frontiers in Endocrinology assesses neurodevelopmental outcomes amongst newborn children presenting with transient or short-term congenital hyperinsulinism. Full article (Source: Society for Endocrinology)
Study: Bisphenol A gets directly through the mouth into the bloodstream (AFP, 13 June 2013)
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A study from France published in Environmental Health Perspectives compares the bioavailability of bisphenol A administered sublingually and orally in dogs. Full article (in German) (Source: Society for Endocrinology)
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MEP calls for parliamentary risk panel to tame green ‘scaremongering’ (Euractiv, 12 June 2013)
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A UK MEP speaking at the European Risk Summit in Dublin, Republic of Ireland, has argued for the formation of a 'formal risk group' within the European Parliament as an advisory panel to lawmakers on contentious issues involving potential risks to human health. Full article (Source: Society for Endocrinology)
British Thyroid Foundation Awards
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The British Thyroid Foundation invites applications each year to its two funding streams, the Evelyn Ashley Smith Awards for Nurses and the Research Award. The two Nurse awards consist of up to £500 to help cover conference/training expenses, including registration fees and /or travel costs, and/or (you may apply to both) £1000 to help support a specific project lasting one year; support an on-going project; or reward a piece of work already completed, but not yet published. The deadline for these awards is 1 July 2013. The Research Award consists of up to £20,000 to support medical research projects directed to the study of thyroid disorders or investigations into the basic understanding of thyroid function. Studies funded through this fun...
Efficacy and Mechanism Evaluation grant: sarcopaenia and its effects on older people
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Applications are sought for research into interventions used in the prevention, diagnosis, management, monitoring or treatment of older people experiencing the effects of sarcopaenia, particularly where sarcopaenia is affecting their health, leading to dependency or impairing recovery from accident, illness or surgery. This commissioned research call is made by the MRC and NIHR Efficacy and Mechanism Evaluation Programme, which aims to bridge preclinical studies and evidence of clinical efficacy. The value of the grant is expected to be in the region of £0.5-2 million. The deadline for applictions is 1 October 2013. More information is available via the link below. http://www.eme.ac.uk/funding/Commissioning.asp (Source: Society for Endocrinology)
NIHR career development competitions
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The National Institute for Health Research (NIHR) has the following competitions open to provide researchers at all stages of their careers with development opportunities in academic medicine: NIHR Clinician Scientist: up to 5 years funding to undertake focussed training and development in order to develop specific skills that will enable a transition from basic research into clinical research or from clinical research into translational and applied research. Deadline: 10 July 2013. NIHR Senior Investigator: Senior Investigators are fundamental to the NIHR Faculty and include some of the country’s foremost researchers, making the most outstanding contribution to clinical and applied health and social care research. Leading researchers funded by the NIHR or the Departme...
Ovarian Cancer Action research grants
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Ovarian Cancer Action, the UK’s leading ovarian cancer charity, has opened a call for new and innovative research grant applications, with the view to starting new and exciting projects in early 2014. A fund of £600,000 over three years has been identified for innovative research that will provide critical pilot data or new insights into the current major scientific challenges in ovarian cancer. Preliminary applications must be submitted by 11:59 on 29 August 2013. For more information please visit the Ovarian Cancer Action website. (Source: Society for Endocrinology)
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MRC Experimental Medicine Challenge Grants
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The Medical Research Council (MRC) invites applications for its Experimental Medicine Challenge Grants, which support ambitious, challenge-led programmes of research into disease pathophysiology in humans. These studies will produce major new mechanistic insights into human disease, with potential application to new therapeutic approaches and opportunities for “reverse translation” to more basic research. In addition to the conventional Experimental Medicine Challenge Grants, applications for smaller “Pathfinder” awards are welcomed. The deadline for outline applications is 25 July 2013. For more information please visit the MRC website. (Source: Society for Endocrinology)
Breast Cancer Campaign pilot grants
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Breast Cancer Campaign invites applications to its pilot grants, to test new hypotheses and generate preliminary data to support a full project grant application. Grants of up to £20,000 are available for up to one year. The deadline for applications is 2 September 2013. For more information on the grants please visit the Breast Cancer Campaign website. (Source: Society for Endocrinology)
Professor, Reader, Senior Lecturer or Lecturer positions in Diabetes, Endocrinology and Metabolism - Imperial College London, UK
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Added via www.naturejobs.com. Imperial College London is making a substantial new investment in Diabetes, Endocrinology and Metabolism. They plan to make senior academic appointments to build upon existing strengths and develop a world-leading translational research programme in collaboration with Imperial College Healthcare NHS Trust. There are major research programmes in gut hormones and obesity, genetics of obesity and diabetes, the pathogenesis of diabetes, mechanisms of thyroid hormone action, and bone and mineral metabolism. They are seeking clinical or non-clinical academics with highly innovative research objectives and a track record of high quality publications. The level of appointment (Professor, Reader, Senior Lecturer or Lecturer) and the generous supporting package will be...
Postdoctoral Research Associates, Institute of Metabolic Science (2/3 posts), University of Cambridge, UK
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Added via NatureJobs. Applications are invited to join the dynamic, internationally recognised team led by Professor Toni Vidal-Puig studying 1) mechanisms of adipose tissue expandability, 2) mechanisms of adipose tissue macrophage polarisation and 3) central and peripheral mechanisms of brown fat activation and thermogenesis (supported by BBSRC and EC FP7 BetaBAT consortium). The successful candidate will hold a PhD in a relevant biological sciences discipline with experience in at least one of the three proposed research areas supported by a proven track record reflected in a strong record of publication. Ideally he/she will have a strong background in in vivo physiology and cellular and molecular biology. Experience in bioinformatics and lipid chemistry is a significant advantage. Cand...
Academic Positions in Veterinary Sciences and Medicine, University of Surrey, UK
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The University of Surrey is currently looking for individuals at Lecturer/Senior Lecturer/Tutor/Senior Tutor levels in a variety of areas, including endocrine systems, to join its new School of Veterinary Medicine which opens in September 2014. The closing date for applications is 12 August 2013. For more information on eligibility criteria for positions at each grade, and to apply, please visit the job advert. (Source: Society for Endocrinology)
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NIHR Clinical Lecturer in Intensive Care Medicine, University of Birmingham, UK
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Added via www.jobs.ac.uk. Applications are invited for the post of NIHR Clinical Lecturer in Intensive Care Medicine (ICM) in the School of Clinical and Experimental Medicine at the University of Birmingham. The main aim of this post is to nurture the academic development of a post-doctoral trainee in ICM, enabling the individual to develop into an independent principal investigator capable of securing a Clinician Scientist Fellowship in the future. The appointee will be expected to contribute significantly to the established research and education programmes of the School, linking the growing speciality of ICM to clinical or health services research; infection, inflammation and immunomodulation; endocrine dysfunction; and trauma and regeneration. Applicants should have completed...
Recognising Low Blood Sugars Could Help Prevent Brain Damage In Newborn Babies
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Researchers from The University of Manchester studying a rare and potentially lethal childhood disease - which is the clinical opposite of diabetes - have made an important discovery. The team has found newborn babies with transient (also known as short-term) congenital hyperinsulinism (CHI) are at risk of developing, long-term disability or brain damage due to low blood sugars. Previously it was thought only babies with the most severe form, known as persistent CHI, were at risk of brain damage... (Source: Health News from Medical News Today)
TEDDY Study Yielding New Approach To Finding High-Risk Genes For Type 1 Diabetes
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Massive samples emanating from a decade-old, international initiative to determine how genetics and environment cause type 1 diabetes are giving scientists a unique perspective on which molecular and environmental factors really contribute to the disease. The TEDDY study, following nearly 9,000 at-risk children from birth to age 15, is enabling scientists to parse which genetic mutations correlate with progression or lack of progression to type 1 diabetes, said Dr... (Source: Health News from Medical News Today)
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Study Suggests Association Between Hypoglycemia, Dementia In Older Adults With Diabetes
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A study of older adults with diabetes mellitus (DM) suggests a bidirectional association between hypoglycemic (low blood glucose) events and dementia, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication. There is a growing body of evidence that DM may increase the risk for developing cognitive impairment, including Alzheimer disease and vascular dementia, and there is research interest in whether DM treatment can prevent cognitive decline... (Source: Health News from Medical News Today)
Overeating And Weight Gain Contributing To Onset Of Diabetes Could Be Related To A Deficit In Reward Circuits In The Brain
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Using positron emission tomography (PET) imaging of the brain, researchers have identified a sweet spot that operates in a disorderly way when simple sugars are introduced to people with insulin resistance, a precursor to type 2 diabetes. For those who have the metabolic syndrome, a sugar drink resulted in a lower-than-normal release of the chemical dopamine in a major pleasure center of the brain. This chemical response may be indicative of a deficient reward system, which could potentially be setting the stage for insulin resistance... (Source: Health News from Medical News Today)
Studies Demonstrate The Strategy To Kill Melanoma Using Diabetes Drugs To Sensitize Resistant Cells
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Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs. (Article link*... (Source: Health News from Medical News Today)
Obesity During Pregnancy Programs Offspring To Be Fat, But Legacy Can Be Overturned
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Scientists in Sydney, Australia, have discovered that obesity and type 2 diabetes in pregnancy can program children to develop metabolic problems later in life. The good news is, this legacy is not set in stone - if children of obese mothers are careful about what they eat, it can be overturned. The study, carried out by scientists at the Victor Chang Cardiac Research Institute, is published in the June edition of the journal Epigenetics. By using genetically identical mice as a model, the team investigated the effects of having a mother with obesity and type 2 diabetes... (Source: Health News from Medical News Today)
Identifying Diabetic Foot Infection And Ruling Out A Non-Infectious Complication That Develops In Nerve-Damaged Joints
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Researchers are kick-starting better diabetic foot care and promoting reduced radiation dose with a new take on a hybrid molecular imaging technique. By targeting both bone cell activity and immune response and improving imaging data interpretation, doctors can better distinguish diabetic foot infection from another common foot condition that often requires an additional bone-marrow scan for definitive diagnosis, say researchers presenting a study at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting... (Source: Health News from Medical News Today)
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Inadequate Noncommunicable Disease Prevention In Low-And Middle-Income Countries
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Nine years after the World Health Organization adopted a global strategy on diet, physical activity, and health to address risk factors for chronic diseases such as heart disease and diabetes (referred to internationally as noncommunicable diseases), only a few low-and middle-income countries have implemented robust national policies to help prevent such diseases, according to a study by international researchers published in this week's PLOS Medicine... (Source: Health News from Medical News Today)
Workers In India Who Walk Or Cycle To Their Job Likely To Be A Healthier Weight
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People in India who walk or cycle to work are less likely to be overweight or obese, according to a study led by Christopher Millett from Imperial College London and the Public Health Foundation of India and colleagues. Their paper reporting the study, published in this week's PLOS Medicine, reveals that cyclists are also less likely to have diabetes or high blood pressure compared to people who take public or private transport to work... (Source: Health News from Medical News Today)
Omega-3 fats from fish oil slash the risk of developing diabetes
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New and undiagnosed cases of diabetes continue to rise at epidemic rates, with as many as one in three men, women and children projected to be affected by the metabolic disorder by 2025. The high circulating blood sugar levels associated with diabetes significantly raise... (Source: NaturalNews.com)
Cocoa may help protect against inflammation, diabetes
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STATE COLLEGE, Pa., June 13 (UPI) -- A few cups of hot cocoa may protect against inflammation, which is linked to obesity and diabetes, U.S. researchers say. (Source: Health News - UPI.com)
BIDMC endocrinology researcher Mark Andermann, Ph.D., named 2013 Pew Scholar
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(Beth Israel Deaconess Medical Center) Mark Andermann, Ph.D., has been named a 2013 Pew Scholar for his work exploring food cues as a new approach to understanding obesity and other eating disorders. (Source: EurekAlert! - Medicine and Health)
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From autism to diabetes to Parkinson's disease
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(Pew Health Group) Pew announces its 2013 class of biomedical scholars. (Source: EurekAlert! - Medicine and Health)
Depression in postmenopausal women may increase diabetes and cardiovascular disease risk
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(University of Massachusetts Medical School) Postmenopausal women who use antidepressant medication or suffer from depression might be more likely to have a higher body mass index, larger waist circumference and inflammation -- all associated with increased risk for diabetes and cardiovascular disease, according to a study led by University of Massachusetts Medical School investigator Yunsheng Ma, Ph.D., M.D., M.P.H. (Source: EurekAlert! - Social and Behavioral Science)
Major hurdle cleared to diabetes transplants
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(Washington University School of Medicine) Researchers at Washington University School of Medicine in St. Louis have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes. (Source: EurekAlert! - Medicine and Health)
Drugmakers to cooperate in safety review of diabetes drugs
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NEW YORK (Reuters) - Global drugmakers said on Wednesday they would cooperate with an independent review to address concerns of a potential link between widely used diabetes medicines and pancreatic cancer and other safety problems. (Source: Reuters: Health)
Inflammation and Diabetic Cognitive Impairment After CEAInflammation and Diabetic Cognitive Impairment After CEA
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Preemptive statin administration might ameliorate inflammation and decrease cognitive risk, the study's lead author says. Medscape Medical News (Source: Medscape Today Headlines)
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New service matches patients with clinical-research trials in Orlando
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In Orlando, more than 550 clinical trials are looking for participants to help find better treatments and cures for such chronic diseases as cancer, AIDS and diabetes. Across Florida, nearly 2,500 studies are looking for subjects. "We have a lot of... (Source: OrlandoSentinel: Medical Research)
Go for a walk after you eat
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Holly Firfer reports that going for a stroll after we eat may help protect us from type 2 diabetes. (Source: CNN.com - Health)